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Although vitamin K has been around for decades, dietary recommendations have been overshadowed by the nominal amount of K1 required for healthy blood clotting—and have ignored the optimal amounts of vitamin K2 needed to maintain healthy bones and arteries at all stage of life.

Today is clear that adequate intake of vitamin K2 is essential for healthy bones and to lower the risk of vascular damage, but it's also clear that almost every one of us is potentially deficient in vitamin K2 due to the change happened in the diet habits and to the modernized food industry (vitamin K2 is nearly nonexistent in junk food).

Symptoms of vitamin K2 deficiency are so common and may be viewed as normal in industrial societies.

VitaMK7® directs calcium to the right places in the body. It functions as a co-factor for activating several Vitamin K-dependent protein in our bodies. Among these the most important are:

  • Osteocalcin in bones, when activated, it facilitates binding of calcium into the bone matrix.
  • Matrix-GLA, which helps to clear the excess calcium away from the blood vessels.

Other K-depend proteins have been classified by organs where the specific protein was generated and by whether Glu residues in the molecule were fully carboxylated or not. All these proteins play a key role to support the positive uptake of calcium in "all-age" people.

In the last decade several studies have highlighted the benefits of vitamin k2 as menaquinone-7 at every stage of life. Maximizing the accretion of bone during growth by optimal nutrition (including vitamin K intake) may reduce the risk of developing osteoporosis.

The association of vitaMK7® natural vitamin K2 as MK7 with other active ingredients with health claims would be suggestable and useful in all age groups, and contributes to bone health.


Childhood & Adolescents

In children and adolescent bone metabolism is highly active and osteocalcin levels are 8 to 10 times higher compared to adult bones - therefore, children require much higher levels of vitamin K2.

Vitamin K2 status in children helps to create strong and healthy bones. In fact research shows children have more inactive osteocalcin, a marker indicating an unusually poor vitamin K status, than adults.

Without adequate vitamin K2, specifically as menaquinone-7 (MK-7), calcium cannot be adequately processed in the body to build healthy, strong bones and accordingly children and adolescent may have the greater benefit from vitamin K2 supplementation.

Young Adults

Maximum skeletal mass is achieved in young adults at 18 - 25 years of age, as a matter of fact up to 90% of peak bone mass is acquired in this age period.

Male and female young adults appear to have the highest level of inactive osteocalcin compared to the total adult group. Decline of ucOC happens at 30 years but levels increase again at 40 years. Without adequate vitamin K2 intake, a significant portion of osteocalcin will stay inactive and unable to bind calcium.

Youth is one of the most important period in which have a proper amount of vitamin k2 working, which means supplementing with vitaMK7® natural vitamin K2 as MK7.

Woman health

Vitamin K2 is an important nutrient for women's health in all stage of life. Most women don't need a calcium supplement, but vitamin K2 will channel dietary calcium to the right places.

Supplemental intake of MK-7 may have benefic effects in the prevention and treatment of bone loss in postmenopausal women and a useful tool in the bone loss with aging.

Most women enter menopause between the ages of 42 and 55. As the levels of estrogen drop dramatically, women undergo rapid bone loss. In the 10 years after menopause, women can lose 40% of their spongy, inner bone and 10% of their hard, outer bone. This reduces bone strength and increases a woman's risk for fracture.

Middle-aged people

The function of vitamin K2 is unique among other vitamins. It activates certain proteins in the body, such as osteocalcin in the bones, Matrix Gla Protein (MGP) in the arteries, and clotting factors in the liver. This means that vitaMK7® natural vitamin K2 as MK7 plays an essential role in the pursuit of cardiovascular and bone health, so strategic in middle age people.

In adults the association between vitamin K status in bone health and vascular elasticity has been extensively studied.

Older people

An increasing number of aging-associated diseases are related to vitamin K2 insufficiency.

Vitamin K2 is crucial for bone health: several studies have demonstrated its role in helping to treat osteoporosis and arthritis.

Vitamin K2 is also associated with the inhibition of arterial calcification and arterial stiffening, which means that increased vitamin K2 intake could be a means of lowering calcium-associated health risks.

In the brain vitamin K2 acts as an antioxidant, helping to prevent free radical-mediated damage, Vitamin K-dependent proteins are now known to play key roles in the central and peripheral nervous systems.

How vitamin K2 deficiency might be a contributing factor to the development of Alzheimer's disease is under evaluation by scientific community.

1. Theuwissen E, et al. Vitamin K status in healthy volunteers. Food Funct. 2014 Feb
2. van Summeren MJ, et al. The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. Br J Nutr. 2009
3. Beulens J, et al. The role of menaquinones (vitamin K2) in human health.Br J Nutr. 2013
4. Ferland G. Vitamin K and the Nervous System: An Overview of its Actions. Advances in Nutrition. 2012

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